发明授权
- 专利标题: DNA encoding CAI resistance proteins and uses thereof
- 专利标题(中): 编码CAI抗性蛋白质的DNA及其用途
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申请号: US900321申请日: 1997-07-25
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公开(公告)号: US5981712A公开(公告)日: 1999-11-09
- 发明人: Elise C. Kohn , Lance A. Liotta , Young Sook Kim
- 申请人: Elise C. Kohn , Lance A. Liotta , Young Sook Kim
- 申请人地址: DC Washington
- 专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址: DC Washington
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; A61K31/70 ; A61K38/00 ; A61K39/395 ; A61K48/00 ; A61P35/00 ; A61P43/00 ; C07H21/04 ; C07K14/47 ; C07K16/18 ; C12N15/09 ; C12N15/12 ; C12N15/52 ; C12P21/02 ; C12P21/08 ; C12Q1/02 ; C12R1/91 ; C07K16/00
摘要:
This invention provides for nucleotide sequences that encode CAIR proteins correlated with cellular resistance to carboxyamido-triazole (CAI) and functionally equivalent compounds. The invention further provides for methods of detecting CAI resistance in biological samples and for cell lines that grow and proliferate in the presence of CAI and functionally equivalent compounds.
公开/授权文献
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