发明授权
US5989545A Clostridial toxin derivatives able to modify peripheral sensory afferent
functions
失效
能够修饰周围感觉传入功能的梭菌毒素衍生物
- 专利标题： Clostridial toxin derivatives able to modify peripheral sensory afferent functions
- 专利标题（中）： 能够修饰周围感觉传入功能的梭菌毒素衍生物
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申请号： US945037申请日： 1998-01-12
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公开(公告)号： US5989545A公开(公告)日： 1999-11-23
- 发明人: Keith Alan Foster , Michael John Duggan , Clifford Charles Shone
- 申请人： Keith Alan Foster , Michael John Duggan , Clifford Charles Shone
- 申请人地址： GBX London GBX Wiltshire
- 专利权人： The Speywood Laboratory Ltd.,Microbiological Research Authority
- 当前专利权人： The Speywood Laboratory Ltd.,Microbiological Research Authority
- 当前专利权人地址： GBX London GBX Wiltshire
- 优先权： GBX9508204 19950421
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K35/74 ; A61K38/00 ; A61K38/16 ; A61K38/22 ; A61K38/46 ; A61K38/48 ; A61K39/395 ; A61K47/48 ; A61P25/00 ; A61P25/04 ; C07K14/33 ; C07K14/48 ; C07K19/00 ; C12N9/52 ; C12N15/31 ; C12N15/62 ; C12P21/02
摘要：
The invention relates to an agent specific for peripheral sensory afferents. The agent may inhibit the transmission of signals between a primary sensory afferent and a projection neuron by controlling the release of at least one neurotransmitter or neuromodulator from the primary sensory afferent. The agent may be used in or as a pharmaceutical for the treatment of pain, particularly chronic pain.
公开/授权文献
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