发明授权
- 专利标题: Recombinant poxvirus-cytomegalovirus, compositions and uses
- 专利标题(中): 重组痘病毒巨细胞病毒,组合物和用途
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申请号: US658665申请日: 1996-06-05
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公开(公告)号: US5997878A公开(公告)日: 1999-12-07
- 发明人: Enzo Paoletti , Steven E. Pincus , William I. Cox , Elizabeth B. Kauffman
- 申请人: Enzo Paoletti , Steven E. Pincus , William I. Cox , Elizabeth B. Kauffman
- 申请人地址: PA Swiftwater
- 专利权人: Connaught Laboratories
- 当前专利权人: Connaught Laboratories
- 当前专利权人地址: PA Swiftwater
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K35/76 ; A61K39/00 ; A61K39/245 ; A61K39/275 ; A61K39/285 ; A61K48/00 ; A61P31/12 ; A61P37/04 ; C07K14/045 ; C07K14/065 ; C07K14/07 ; C07K14/145 ; C07K16/08 ; C12N7/00 ; C12N7/01 ; C12N15/00 ; C12P21/02
摘要:
Attenuated recombinant viruses containing DNA encoding an HCMV antigen, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The recombinant viruses and gene products therefrom and antibodies generated by the viruses and gene products have several preventive, therapeutic and diagnostic uses. The DNA of the recombinant viruses can be used as probes or for generating PCR primers.
公开/授权文献
- US5290378A Method for preparing a rubber-based composite material 公开/授权日:1994-03-01