发明授权
- 专利标题: Phosphorous containing benzothiophenes for treating estrogen deficiency
- 专利标题(中): 含磷苯并噻吩用于治疗雌激素缺乏症
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申请号: US946842申请日: 1997-10-08
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公开(公告)号: US5998443A公开(公告)日: 1999-12-07
- 发明人: Henry U. Bryant , Jeffrey A. Dodge , Jeffrey S. Nissen
- 申请人: Henry U. Bryant , Jeffrey A. Dodge , Jeffrey S. Nissen
- 申请人地址: IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: IN Indianapolis
- 主分类号: C07D333/56
- IPC分类号: C07D333/56 ; A61K31/38 ; A61K31/381 ; A61K31/4433 ; A61K31/445 ; A61K31/67 ; A61K31/675 ; A61P13/02 ; A61P15/00 ; A61P19/10 ; A61P35/00 ; A61P43/00 ; C07D409/12 ; C07F9/6553 ; C07F9/6558 ; C07D409/10
摘要:
This invention relates to the fields of pharmaceutical and organic chemistry and provides novel phosphorous-containing benzothiophene compounds which are useful for the treatment of the various medical indications associated with post-menopausal syndrome, as well as estrogen dependent diseases including cancer of the breast, uterus and cervix. The present invention further relates to intermediate compounds and processes useful for preparing the pharmaceutically active compounds of the present invention, and pharmaceutical compositions.
公开/授权文献
- US4914198A Novel substance UCY1003 and process for preparing the same 公开/授权日:1990-04-03
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