发明授权
- 专利标题： Methods of screening for ulcerative colitis and Crohn's disease
- 专利标题（中）： 筛查溃疡性结肠炎和克罗恩病的方法
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申请号： US933824申请日： 1997-09-19
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公开(公告)号： US6008335A公开(公告)日： 1999-12-28
- 发明人: Jerome I. Rotter , Stephan R. Targan , Huiying Yang , Arthur L. Beaudet , Devendra Vora
- 申请人： Jerome I. Rotter , Stephan R. Targan , Huiying Yang , Arthur L. Beaudet , Devendra Vora
- 申请人地址： CA Los Angeles
- 专利权人： Cedars-Sinai Medical Center
- 当前专利权人： Cedars-Sinai Medical Center
- 当前专利权人地址： CA Los Angeles
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K16/28 ; C12Q1/68 ; C07H21/02 ; C07H21/04
摘要：
A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.
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