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公开(公告)号：US6008335A
公开(公告)日：1999-12-28
申请号：US933824
申请日：1997-09-19
IPC分类号： C07K14/705 , C07K16/28 , C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C07K16/2821 , C07K14/70525 , C12Q1/6883 , C12Q2600/156
摘要： A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.
摘要翻译： 已经发现了IBD与ICAM-1氨基酸残基241之间的多态性的新型关联。 根据本发明，提供了筛选IBD的方法，用于治疗IBD的方法，与由R241等位基因编码的ICAM-1特异性反应的抗体以及利用本发明方法的试剂盒。
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公开(公告)号：US06884590B1
公开(公告)日：2005-04-26
申请号：US09419408
申请日：1999-10-15
IPC分类号： C07K14/705 , C07K16/28 , C12Q1/68 , G01N33/53
CPC分类号： C12Q1/6883 , C07K14/70525 , C07K16/2821 , C12Q2600/156
摘要： A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.
摘要翻译： 已经发现了IBD与ICAM-1氨基酸残基241之间的多态性的新型关联。 根据本发明，提供了筛选IBD的方法，用于治疗IBD的方法，与由R241等位基因编码的ICAM-1特异性反应的抗体以及利用本发明方法的试剂盒。
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公开(公告)号：US5681699A
公开(公告)日：1997-10-28
申请号：US196003
申请日：1994-02-11
IPC分类号： C07K14/705 , C07K16/28 , C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C07K16/2821 , C07K14/70525 , C12Q1/6883 , C12Q2600/156
摘要： A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive wish ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.
摘要翻译： 已经发现了IBD与ICAM-1氨基酸残基241之间的多态性的新型关联。 根据本发明，提供了筛选IBD的方法，用于治疗IBD的方法，由R241等位基因编码的抗体特异性反应性愿望ICAM-1和利用本发明方法的试剂盒。
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