Invention Grant
- Patent Title: In vivo and in vitro model of cutaneous photoaging
- Patent Title (中): 皮肤光老化的体内和体外模型
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Application No.: US973449Application Date: 1997-12-23
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Publication No.: US6018098APublication Date: 2000-01-25
- Inventor: Eric F. Bernstein , Jouni Uitto
- Applicant: Eric F. Bernstein , Jouni Uitto
- Applicant Address: PA Philadelphia
- Assignee: Thomas Jefferson University
- Current Assignee: Thomas Jefferson University
- Current Assignee Address: PA Philadelphia
- Main IPC: A61K49/00
- IPC: A61K49/00 ; C12N15/00 ; C12N15/85 ; C12Q1/00
Abstract:
A transgenic mouse capable of expressing a reporter gene regulated by human elastin promoter is provided. Mouse fibroblast cultures derived from this transgenic mouse are also provided. In addition, methods of identifying compounds capable of inhibiting cutaneous photodamage with this transgenic mouse or fibroblast cultures derived from these mice are provided.
Public/Granted literature
- US5298051A Method of modifying ceramic composite bodies by a post-treatment process and articles produced thereby Public/Granted day:1994-03-29
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