发明授权
US6022704A DNA and mRNA encoding an .alpha..sub.4 subunit of human neuronal
nicotinic acetylcholine receptor and cells transformed with same
失效
编码人神经元烟碱乙酰胆碱受体的α4亚基的DNA和mRNA以及用其转化的细胞
- 专利标题： DNA and mRNA encoding an .alpha..sub.4 subunit of human neuronal nicotinic acetylcholine receptor and cells transformed with same
- 专利标题（中）： 编码人神经元烟碱乙酰胆碱受体的α4亚基的DNA和mRNA以及用其转化的细胞
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申请号： US467574申请日： 1995-06-05
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公开(公告)号： US6022704A公开(公告)日： 2000-02-08
- 发明人: Kathryn J. Elliott , Steven B. Ellis , Michael M. Harpold
- 申请人： Kathryn J. Elliott , Steven B. Ellis , Michael M. Harpold
- 申请人地址： CA LaJolla
- 专利权人： SIBIA Neurosciences, Inc.
- 当前专利权人： SIBIA Neurosciences, Inc.
- 当前专利权人地址： CA LaJolla
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; C07K14/705 ; C07K14/715 ; C07K16/28 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12P21/08 ; C12Q1/00 ; C12Q1/02 ; C12Q1/68 ; C12R1/91 ; G01N33/15 ; C12N15/00
摘要：
DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said DNA, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically .alpha..sub.4 and .alpha..sub.7) and beta subunits (specifically .beta..sub.4) are provided. In addition, combinations of subunits (i.e., .alpha..sub.1, .alpha..sub.2, .alpha..sub.3, .alpha..sub.4, and/or .alpha..sub.7 subunits in combination with .beta..sub.4 subunits; or .beta..sub.2, .beta..sub.3 and/or .beta..sub.4 subunits in combination with .alpha..sub.4 and/or .alpha..sub.7 subunits) are provided.
公开/授权文献
- USD333098S Bottle 公开/授权日：1993-02-09
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