发明授权
US6036974A Method and apparatus for preparation of molded tablet and thereby
prepared molded tablet
失效
用于制备模塑片剂的方法和设备,从而制备模塑片剂
- 专利标题: Method and apparatus for preparation of molded tablet and thereby prepared molded tablet
- 专利标题(中): 用于制备模塑片剂的方法和设备,从而制备模塑片剂
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申请号: US127555申请日: 1993-09-28
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公开(公告)号: US6036974A公开(公告)日: 2000-03-14
- 发明人: Yuki Tsushima , Kazuhide Ashizawa , Sumio Watanabe
- 申请人: Yuki Tsushima , Kazuhide Ashizawa , Sumio Watanabe
- 申请人地址: JPX Tokyo
- 专利权人: Eisai Co. Ltd.
- 当前专利权人: Eisai Co. Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX4-287037 19921002; JPX4-345115 19921202; JPX5-236266 19930922
- 主分类号: A61J3/10
- IPC分类号: A61J3/10 ; A61K9/20 ; B30B11/02
摘要:
Active ingredients such as medicines are mixed with excipient and then kneaded together with binder and solvent such as alcohol or water to prepare a wetted paste. A mold is filled with this paste. Top and bottom surfaces of the paste within the mold are coated with powder such as lubricant in order to avoid possible sticking of the paste to the apparatus during a subsequent compression step. Then a compressive pressure is exerted on the surface of the paste. Thereafter, the tablet is taken from the mold. The molded tablet can contain water-soluble or fat-soluble medicine.
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