发明授权
US6040290A Ligand growth factor gp30 that binds to the erbB-2 receptor protein and
induces cellular responses
失效
配体生长因子gp30结合erbB-2受体蛋白并诱导细胞反应
- 专利标题: Ligand growth factor gp30 that binds to the erbB-2 receptor protein and induces cellular responses
- 专利标题(中): 配体生长因子gp30结合erbB-2受体蛋白并诱导细胞反应
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申请号: US703089申请日: 1996-08-26
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公开(公告)号: US6040290A公开(公告)日: 2000-03-21
- 发明人: Marc E. Lippman , Ruth Lupu
- 申请人: Marc E. Lippman , Ruth Lupu
- 申请人地址: DC Washington
- 专利权人: Georgetown University
- 当前专利权人: Georgetown University
- 当前专利权人地址: DC Washington
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K51/08 ; C07K14/475 ; C07K14/495 ; C07K14/705 ; C07K14/71 ; C07K16/22 ; C07K19/00 ; G01N33/566 ; G01N33/574 ; G01N33/68 ; G01N33/74 ; A61K38/18 ; C07K17/02
摘要:
The present invention relates to erbB-2 ligands and functional derivatives thereof which are capable of binding to the erbB-2 oncogene product. The present invention further pertains to anti-ligand molecules capable of recognizing and binding to the erbB-2 ligand molecule and to screening assays for such ligands. The present invention additionally relates to uses for the erbB-2 ligand, the anti-ligand molecules and the screening assays. The present invention also pertains to a method for inhibiting the growth of adenocarcinoma cells.
公开/授权文献
- US5186553A Printer and method 公开/授权日:1993-02-16
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