- 专利标题： Anti-herpesvirus compounds and methods for identifying, making and using same
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申请号： US759201申请日： 1996-12-04
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公开(公告)号： US6057451A公开(公告)日： 2000-05-02
- 发明人: James J. Crute , Anne-Marie Faucher , Christine A. Grygon , Karl D. Hargrave , Bruno Simoneau , Bounkham Thavonekham
- 申请人： James J. Crute , Anne-Marie Faucher , Christine A. Grygon , Karl D. Hargrave , Bruno Simoneau , Bounkham Thavonekham
- 申请人地址： CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址： CT Ridgefield
- 主分类号： C07D277/20
- IPC分类号： C07D277/20 ; A61K31/00 ; A61K31/425 ; A61K31/426 ; A61K31/427 ; A61K31/44 ; A61K31/4427 ; A61K31/4439 ; A61K31/445 ; A61K31/4465 ; A61K31/4523 ; A61K31/454 ; A61K31/495 ; A61K31/4965 ; A61K31/497 ; A61K31/505 ; A61K31/506 ; A61P31/00 ; A61P31/22 ; C07D277/24 ; C07D277/28 ; C07D277/30 ; C07D277/40 ; C07D277/42 ; C07D277/44 ; C07D277/46 ; C07D277/48 ; C07D417/12 ; C07D417/14 ; C07D521/00 ; C07D277/00 ; A61K31/38 ; C07D277/04
摘要：
This invention relates to methods for inhibiting herpes replication and for treating herpes infection in a mammal by inhibiting the herpes helicase-primase enzyme complex. This invention also relates to thiazolyphenyl derivatives that inhibit the herpes helicase-primase and to pharmaceutical compositions comprising the thiazolylphenyl derivatives, to methods of using and methods of producing the thiazolylphenyl derivatives.
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