发明授权
- 专利标题： Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
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申请号： US844138申请日： 1997-04-18
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公开(公告)号： US6060082A公开(公告)日： 2000-05-09
- 发明人: Hongming Chen , Robert S. Langer
- 申请人： Hongming Chen , Robert S. Langer
- 申请人地址： MA Cambridge
- 专利权人： Massachusetts Institute of Technology
- 当前专利权人： Massachusetts Institute of Technology
- 当前专利权人地址： MA Cambridge
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K38/28 ; A61K39/00 ; A61K39/05 ; A61K48/00
摘要：
The present invention relates to targeted polymerized liposomes for oral and/or mucosal delivery of vaccines, allergens and therapeutics. In particular, the present invention relates to polymerized liposomes which have been modified on their surface to contain a molecule or ligand which targets the polymerized liposome to a specific site or cell type. More particularly, the invention relates to the use of polymerized liposomes modified to contain a carbohydrate or lectin on their surface.
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