发明授权
US06066634A Substituted condensation products of N-benzyl-3-indenylacetamides
heterocyclic aldehydes for neoplasia
失效
N-苄基-3-茚基乙酰胺杂环醛用于瘤形成的缩合产物
- 专利标题： Substituted condensation products of N-benzyl-3-indenylacetamides heterocyclic aldehydes for neoplasia
- 专利标题（中）： N-苄基-3-茚基乙酰胺杂环醛用于瘤形成的缩合产物
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申请号： US206245申请日： 1998-12-07
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公开(公告)号： US06066634A公开(公告)日： 2000-05-23
- 发明人: Gerhard J. Sperl , Paul Gross , Klaus Brendel , Gary A. Piazza , Rifat Pamukcu
- 申请人： Gerhard J. Sperl , Paul Gross , Klaus Brendel , Gary A. Piazza , Rifat Pamukcu
- 申请人地址： PA Horsham AZ Tuscon
- 专利权人： Cell Pathways, Inc.,University of Arizona
- 当前专利权人： Cell Pathways, Inc.,University of Arizona
- 当前专利权人地址： PA Horsham AZ Tuscon
- 主分类号： C07D213/56
- IPC分类号： C07D213/56 ; C07D215/14 ; C07D237/08 ; C07D239/26 ; C07D241/12 ; A61K31/34 ; A61K31/38 ; A61K31/4409 ; A61K31/47
摘要：
Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes are useful for inducing or promoting apotosis and for arresting uncontrolled neoplastic cell proliferation, and are specifically useful in the arresting and treatment of neoplasias, including precancerous and cancerous lesions.
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