发明授权
US6090378A Composition comprising interleukin-2 and thymidine kinase for the
treatment of tumors
失效
包含用于治疗肿瘤的白细胞介素-2和胸苷激酶的组合物
- 专利标题： Composition comprising interleukin-2 and thymidine kinase for the treatment of tumors
- 专利标题（中）： 包含用于治疗肿瘤的白细胞介素-2和胸苷激酶的组合物
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申请号： US895588申请日： 1997-07-16
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公开(公告)号： US6090378A公开(公告)日： 2000-07-18
- 发明人: Claude Roth , Philippe Kourilsky , Lluis Mir , David Klatzmann , Jean-Loup Salzmann
- 申请人： Claude Roth , Philippe Kourilsky , Lluis Mir , David Klatzmann , Jean-Loup Salzmann
- 申请人地址： FRX Paris FRX Paris FRX Paris FRX Paris
- 专利权人： Institut Pasteur,Institut National de la Sante et de la Recherche Medicale,Universite Pierre et Marie Curie,Assistance Publique-Hopitaux de Paris
- 当前专利权人： Institut Pasteur,Institut National de la Sante et de la Recherche Medicale,Universite Pierre et Marie Curie,Assistance Publique-Hopitaux de Paris
- 当前专利权人地址： FRX Paris FRX Paris FRX Paris FRX Paris
- 优先权： FRX9302012 19930222
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/70 ; A61K35/12 ; A61K35/74 ; A61K35/76 ; A61K38/00 ; A61K38/20 ; A61K38/21 ; A61K38/45 ; A61K38/46 ; A61K48/00 ; A61P35/00
摘要：
Composition for use in the treatment of tumors and the immunization of humans or animals comprising a synergistic association of cells, viruses, or bacteria expressing, transitorily, in organisms at least one gene for producing in vivo one or more immunomodulators, and viruses, or cells producing viruses, said viruses preferably infecting dividing cells of the treated organisms and carrying within their genome at least one gene whose expression in the dividing cells will cause their destruction.
公开/授权文献
- US5283342A Biotinylated small molecules 公开/授权日：1994-02-01
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