发明授权
US6090916A Nematode-extracted serine protease inhibitors and anticoagulant proteins
失效
线虫提取的丝氨酸蛋白酶抑制剂和抗凝血蛋白
- 专利标题： Nematode-extracted serine protease inhibitors and anticoagulant proteins
- 专利标题（中）： 线虫提取的丝氨酸蛋白酶抑制剂和抗凝血蛋白
-
申请号： US809455申请日： 1997-11-24
-
公开(公告)号： US6090916A公开(公告)日： 2000-07-18
- 发明人: George Phillip Vlasuk , Patrick Eric Hugo Stanssens , Joris Hilda Lieven Messens , Marc Josef Lauwereys , Yves Rene LaRoche , Laurent Stephane Jespers , Yannick Georges Jozef Gansemans , Matthew Moyle , Peter W. Bergum
- 申请人： George Phillip Vlasuk , Patrick Eric Hugo Stanssens , Joris Hilda Lieven Messens , Marc Josef Lauwereys , Yves Rene LaRoche , Laurent Stephane Jespers , Yannick Georges Jozef Gansemans , Matthew Moyle , Peter W. Bergum
- 申请人地址： CA San Diego
- 专利权人： Corvas International, Inc.
- 当前专利权人： Corvas International, Inc.
- 当前专利权人地址： CA San Diego
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K35/56 ; A61K38/00 ; A61P7/02 ; C07K14/81 ; C12N9/99 ; C12N15/12 ; C12N15/19 ; C07K1/00
摘要：
Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.
公开/授权文献
信息查询
IPC分类:
