发明授权
US6093836A 1,3-diphenylpropane derivatives having inhibitory activity against
tyrosinase and process for preparation thereof
失效
对酪氨酸酶具有抑制活性的1,3-二苯基丙烷衍生物及其制备方法
- 专利标题： 1,3-diphenylpropane derivatives having inhibitory activity against tyrosinase and process for preparation thereof
- 专利标题（中）： 对酪氨酸酶具有抑制活性的1,3-二苯基丙烷衍生物及其制备方法
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申请号： US180352申请日： 1998-11-06
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公开(公告)号： US6093836A公开(公告)日： 2000-07-25
- 发明人: Young Ho Rhee , Kyung Ae Kim , Hyun Ho Lee , Jong Kwon Choi , Sang Hwa Lee
- 申请人： Young Ho Rhee , Kyung Ae Kim , Hyun Ho Lee , Jong Kwon Choi , Sang Hwa Lee
- 申请人地址： KRX Seoul
- 专利权人： LG Chemical Ltd.
- 当前专利权人： LG Chemical Ltd.
- 当前专利权人地址： KRX Seoul
- 优先权： KRX97/7452 19970306
- 主分类号： C07D311/72
- IPC分类号： C07D311/72 ; A61K8/00 ; A61K8/33 ; A61Q19/00 ; C07C37/055 ; C07C39/12 ; C07C39/15 ; C07C41/26 ; C07C43/23 ; C07C45/62 ; C07C45/74 ; C07C49/83 ; C07C49/84 ; C07D311/58 ; C07C43/205 ; C07C49/303 ; C07C49/603
摘要：
The present invention relates to a novel 1,3-diphenylpropane derivative having an inhibitory activity against tyrosinase represented by the following formula (I): ##STR1## in which - - represents double or single bond,R.sub.1 represents hydrogen or C.sub.1 -C.sub.10 alkyl,R.sub.2 represents C.sub.1 -C.sub.5 alkyl or C.sub.1 -C.sub.5 alkoxyalkyl, orR.sub.1 and R.sub.2 together represent a 5 to 6 membered heterocycle which can be substituted by C.sub.1 -C.sub.5 alkyl and which contains oxygen as the hetero atom,R.sub.3 represents hydrogen or C.sub.1 -C.sub.7 alkyl,R.sub.4 represents hydrogen, hydroxy, or oxo, andR.sub.5 and R.sub.6 mindependently of one another represent hydrogen or C.sub.1 -C.sub.5 alkyl.
公开/授权文献
- US4300541A Speculum lens structure 公开/授权日：1981-11-17
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