发明授权
US6100061A Recombinant cell clone having increased stability in serum- and
protein-free medium and a method of recovering the stable cell clone
and the production of recombinant proteins by using a stable cell clone
失效
在无血清和无蛋白质培养基中具有增加的稳定性的重组细胞克隆和通过使用稳定的细胞克隆来恢复稳定的细胞克隆和重组蛋白的产生的方法
- 专利标题： Recombinant cell clone having increased stability in serum- and protein-free medium and a method of recovering the stable cell clone and the production of recombinant proteins by using a stable cell clone
- 专利标题（中）： 在无血清和无蛋白质培养基中具有增加的稳定性的重组细胞克隆和通过使用稳定的细胞克隆来恢复稳定的细胞克隆和重组蛋白的产生的方法
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申请号： US100253申请日： 1998-06-19
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公开(公告)号： US6100061A公开(公告)日： 2000-08-08
- 发明人: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人： Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人地址： ATX Vienna
- 专利权人： Immuno Aktiengesellschaft
- 当前专利权人： Immuno Aktiengesellschaft
- 当前专利权人地址： ATX Vienna
- 优先权： ATX1073/97 19970620
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12P21/02 ; C12N5/10
摘要：
Disclosed are a stable recombinant cell clone which is stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
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