- 专利标题： Glycosylated analogs of fusidic acid
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申请号： US623335申请日： 1996-03-27
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公开(公告)号： US6103884A公开(公告)日： 2000-08-15
- 发明人: Masato Koreeda , Roeland Tuinman , Brian Keith Shull
- 申请人： Masato Koreeda , Roeland Tuinman , Brian Keith Shull
- 申请人地址： MI
- 专利权人： The University of Michigan
- 当前专利权人： The University of Michigan
- 当前专利权人地址： MI
- 主分类号： A61K31/56
- IPC分类号： A61K31/56 ; A61K31/70 ; A61K31/704 ; C07H1/00 ; C07H15/00 ; C07J1/00
摘要：
Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient of choice as compared to unmodified fusidic acid. Certain glycosylated analogs may be employed as chemotherapeutic agents and particular analogs may be useful for fighting anti-microbial infections.
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