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公开(公告)号：US06462182B1
公开(公告)日：2002-10-08
申请号：US09616658
申请日：2000-07-14
IPC分类号： C07H1500
摘要： Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient of choice as compared to unmodified fusidic acid. Certain glycosylated analogs may be employed as chemotherapeutic agents and particular analogs may be useful for fighting anti-microbial infections.
摘要翻译： 描述了连接一个或多个碳水化合物单元的夫西地酸的新型类似物。 与未修饰的夫西地酸相比，夫西地酸的某些糖基化类似物具有增强的稀释剂或赋形剂的溶解性。 某些糖基化类似物可用作化学治疗剂，特定的类似物可用于抗菌抗感染。
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公开(公告)号：US6103884A
公开(公告)日：2000-08-15
申请号：US623335
申请日：1996-03-27
摘要： Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient of choice as compared to unmodified fusidic acid. Certain glycosylated analogs may be employed as chemotherapeutic agents and particular analogs may be useful for fighting anti-microbial infections.
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公开(公告)号：US06720307B2
公开(公告)日：2004-04-13
申请号：US10189242
申请日：2002-07-02
IPC分类号： A61K3170
摘要： Novel analogs of fusidic acid are described with one or more carbohydrate units attached. Certain glycosylated analogs of fusidic acid have enhanced solubility properties in diluents or excipient of choice as compared to unmodified fusidic acid. Certain glycosylated analogs may be employed as chemotherapeutic agents and particular analogs may be useful for fighting anti-microbial infections.
摘要翻译： 描述了连接一个或多个碳水化合物单元的夫西地酸的新型类似物。 与未修饰的夫西地酸相比，夫西地酸的某些糖基化类似物具有增强的稀释剂或赋形剂的溶解性。 某些糖基化类似物可用作化学治疗剂，特定的类似物可用于抗菌感染。
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公开(公告)号：US20050181152A1
公开(公告)日：2005-08-18
申请号：US10710494
申请日：2004-07-15
申请人： Sharon Free , C. Galbraith , Roeland Tuinman , Andrew Thompson
发明人： Sharon Free , C. Galbraith , Roeland Tuinman , Andrew Thompson
CPC分类号： B60K15/03 , B60K15/00 , B60K2015/03381 , B64D37/32 , B65D90/42 , C08G18/4072 , C08G2101/0008 , C08G2101/005 , C08G2101/0083 , C08G2390/00 , Y02T50/44 , Y10T428/13
摘要： A reticulated polyurethane foam having a density less than 1.0 pounds per cubic foot [16 kg/m3] forms an explosion suppressing material that is installed into the inner volume of a fuel tank to fill from 50 to 90% or up to 100% of the volume of such tank. The reticulated polyurethane foam has particular advantage when used in a fuel tank for an aircraft.
摘要翻译： 密度小于1.0磅/立方英尺[16kg / m 3]的网状聚氨酯泡沫塑料形成防爆材料，其被安装在燃料箱的内部容积中以填充50至90 ％或高达这种罐体积的100％。 当用于飞机的燃料箱时，网状聚氨酯泡沫具有特别的优点。
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5.发明授权Use of low unsaturated polyether polyols in high resilience slabstock foam applications 失效在高弹性板坯泡沫应用中使用低不饱和聚醚多元醇公开(公告)号：US06201035B1
公开(公告)日：2001-03-13
申请号：US09578208
申请日：2000-05-24
IPC分类号： C08G1848
CPC分类号： C08G18/4866 , C08G18/4072 , C08G18/4816 , C08G2101/0008 , C08G2101/005 , C08G2101/0083 , Y10S521/914
摘要： The present invention discloses a method for the formation of and a flexible slabstock polyurethane foam having substantially improved indentation force deflection and resilience characteristics while maintaining the other physical properties. The method comprises the steps of: forming a polyol blend having a nominal functionality of at least 2.3 by combining at least one polyether polyol having a plurality of terminal ethylene oxide caps of from 5 to 25% by weight based on the total weight of the polyether polyol, a molecular weight of greater than or equal to 4000 Daltons, and an unsaturation of greater than 0.04 meq/g KOH; at least one graft polyether polyol having an equivalent weight of greater than 1000 Daltons, a solids content of at least 28%, and a plurality of terminal ethylene oxide caps of from 5 to 25% by weight based on the total weight of the graft polyether polyol; and at least one very low unsaturated polyether polyol having an unsaturation of less than or equal to 0.018 meq/g KOH and a plurality of terminal ethylene oxide caps of from 5 to 25% by weight based on the total weight of the polyether polyol; providing at least one polyisocyanate component; providing a catalyst; providing water as a blowing agent at a level of between 3 to 7% by weight; and combining the polyol blend with the polyisocyanate component, the catalyst and the water to form a slabstock polyurethane foam.
摘要翻译： 本发明公开了一种用于形成柔性板坯聚氨酯泡沫的方法，其具有显着改善的压痕力偏转和弹性特性，同时保持其它物理性能。 该方法包括以下步骤：通过组合至少一种具有多个端基环氧乙烷盖的聚醚多元醇形成多元醇共混物，所述多元醇共混物具有至少2.3的标称官能度，基于聚醚的总重量为5至25重量％ 多元醇，分子量大于或等于4000道尔顿，不饱和度大于0.04meq / g KOH; 至少一种接枝聚醚多元醇，其当量重量大于1000道尔顿，固体含量至少为28％，多个末端环氧乙烷盖为5至25重量％，基于接枝聚醚的总重量 多元醇 和至少一种具有小于或等于0.018meq / g KOH的不饱和度的非常低的不饱和聚醚多元醇和基于聚醚多元醇总重量的5至25重量％的多个末端环氧乙烷盖; 提供至少一种多异氰酸酯组分; 提供催化剂; 以3至7重量％的水平提供水作为发泡剂; 并将多元醇共混物与多异氰酸酯组分，催化剂和水混合以形成板块聚氨酯泡沫。
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6.发明授权公开(公告)号：US06344494B1
公开(公告)日：2002-02-05
申请号：US09579239
申请日：2000-05-24
IPC分类号： C08G1814
CPC分类号： C08G18/4841 , C08G18/4866 , C08G2101/0008 , C08G2101/005 , C08G2101/0083
摘要： The present invention discloses a method for the formation of a flexible slabstock polyurethane foam having substantially improved indentation force deflection and resilience characteristics while maintaining the other physical properties. The method comprises the steps of reacting a triol polyoxyalkylene polyether polyol having a plurality of internal blocks formed from oxyalkylene monomers with a plurality of terminal caps comprising ethylene oxide attached to said plurality of internal blocks, the internal blocks containing at least 80% by weight propylene oxide based on the total weight of all of the oxyalkylenes in said internal blocks and the amount of ethylene oxide in the terminal caps comprising from 5 to 25% by weight based on the total weight of the polyol, said polyol having a degree of unsaturation of less than or equal to 0.015 meq/g KOH with a polyisocyanate component in the presence of a catalyst and water as a blowing agent at a level of between 3 to 7% by weight.
摘要翻译： 本发明公开了一种用于形成柔性板状聚氨酯泡沫的方法，其具有显着改善的压痕力偏转和弹性特性，同时保持其它物理特性。 该方法包括使具有多个由氧化烯单体形成的多个内部嵌段的三醇聚氧化烯聚醚多元醇与多个连接到所述多个内部嵌段上的环氧乙烷的端帽反应的步骤，内部嵌段含有至少80重量％的丙烯 氧化物，基于所述内部嵌段中所有的氧化烯的总重量，末端盖中的环氧乙烷的量为5至25重量％，基于多元醇的总重量，所述多元醇的不饱和度为 在催化剂存在下，多异氰酸酯成分的含量小于或等于0.015meq / g KOH，发泡剂水为3〜7重量％。
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