发明授权
US6121330A 5-Hydroxyalkyl substituted phenyls and their use in medicaments for the
treatment of arteriosclerosis and hyperlipoproteinaemia
失效
5-羟基烷基取代的苯基及其用于治疗动脉硬化和高脂蛋白血症的药物
- 专利标题： 5-Hydroxyalkyl substituted phenyls and their use in medicaments for the treatment of arteriosclerosis and hyperlipoproteinaemia
- 专利标题（中）： 5-羟基烷基取代的苯基及其用于治疗动脉硬化和高脂蛋白血症的药物
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申请号： US341983申请日： 1999-09-02
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公开(公告)号： US6121330A公开(公告)日： 2000-09-19
- 发明人: Matthias Muller-Gliemann , Rolf Angerbauer , Arndt Brandes , Michael Logers , Carsten Schmeck , Gunter Schmidt , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt
- 申请人： Matthias Muller-Gliemann , Rolf Angerbauer , Arndt Brandes , Michael Logers , Carsten Schmeck , Gunter Schmidt , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt
- 申请人地址： DEX Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DEX Leverkusen
- 优先权： DEX19704244 19970205
- 主分类号： A61P3/06
- IPC分类号： A61P3/06 ; A61K31/045 ; A61K31/075 ; A61K31/12 ; A61P9/10 ; C07C27/02 ; C07C33/26 ; C07C33/34 ; C07C33/46 ; C07C33/50 ; C07C43/178 ; C07C49/83 ; C07C67/31 ; C07C67/343 ; C07C69/74 ; C07C69/76 ; C07C303/28 ; C07C309/65 ; C07C41/00 ; C07C49/76
摘要：
The novel 5-hydroxy-alkyl-substituted phenyls are prepared by either reacting the corresponding benzaldehydes with the Grignard compounds and subsequently reducing the other functional groups or by reducing the corresponding benzoic esters by customary methods to give the corresponding hydroxyl compounds. The 5-hydroxy-alkyl-substituted phenyls are suitable for use as active compounds in medicaments, in particular for the treatment of dyslipidaemia.
公开/授权文献
- US5501336A Generic goods-containing crate 公开/授权日：1996-03-26
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