发明授权
US6140100A Cell-targeting molecule comprising a mutant human carboxypeptidase A
失效
包含突变型人羧肽酶A的细胞靶向分子
- 专利标题: Cell-targeting molecule comprising a mutant human carboxypeptidase A
- 专利标题(中): 包含突变型人羧肽酶A的细胞靶向分子
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申请号: US640906申请日: 1996-05-09
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公开(公告)号: US6140100A公开(公告)日: 2000-10-31
- 发明人: Gary Keith Smith , Todd Andrew Blumenkopf , Michael Cory
- 申请人: Gary Keith Smith , Todd Andrew Blumenkopf , Michael Cory
- 申请人地址: NC Research Triangle Park
- 专利权人: Glaxo Wellcome Inc.
- 当前专利权人: Glaxo Wellcome Inc.
- 当前专利权人地址: NC Research Triangle Park
- 优先权: GBX9323429 19931112
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K47/48 ; C12N1/19 ; C12N9/48 ; C12N9/64 ; C12N9/96 ; C12N15/57 ; C12R1/865 ; C12N15/62 ; C12N15/79
摘要:
Conjugates of a cell targetting molecule and a mutant human carboxypeptidase A enzyme are provided. Suitable targetting molecules include antibodies, hormones, ligands, cytokines, antigens, oligonucleotides and peptidomimetics. Enzymes comprising a mutant human carboxypeptidase A enzyme are also provided.
公开/授权文献
- US5098614A Adjustable bubble bend 公开/授权日:1992-03-24
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