发明授权
US6140124A Antisense modulation of P38 mitogen activated protein kinase expression
有权
P38丝裂原活化蛋白激酶表达的反义调制
- 专利标题： Antisense modulation of P38 mitogen activated protein kinase expression
- 专利标题（中）： P38丝裂原活化蛋白激酶表达的反义调制
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申请号： US286904申请日： 1999-04-06
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公开(公告)号： US6140124A公开(公告)日： 2000-10-31
- 发明人: Brett P. Monia , William A. Gaarde , Pamela S. Nero , Robert McKay
- 申请人： Brett P. Monia , William A. Gaarde , Pamela S. Nero , Robert McKay
- 申请人地址： CA Carlsbad
- 专利权人： Isis Pharmaceuticals Inc.
- 当前专利权人： Isis Pharmaceuticals Inc.
- 当前专利权人地址： CA Carlsbad
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/711 ; A61K38/00 ; A61P19/02 ; A61P29/00 ; A61P37/06 ; A61P43/00 ; C12N5/10 ; C12N9/99 ; C12N15/113 ; C07H21/04 ; C07H21/02 ; C12N5/00 ; C12Q1/68
摘要：
Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for the treatment and diagnosis of diseases or conditions associated with aberrant expression of one or more p38 MAPKs are also provided.
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