发明授权
- 专利标题: Method for inhibiting the growth of mammalian cells
- 专利标题(中): 抑制哺乳动物细胞生长的方法
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申请号: US939516申请日: 1997-09-29
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公开(公告)号: US6140362A公开(公告)日: 2000-10-31
- 发明人: Enrique Luis Michelotti , David Hamilton Young
- 申请人: Enrique Luis Michelotti , David Hamilton Young
- 申请人地址: PA Philadelphia
- 专利权人: Rohm and Haas Company
- 当前专利权人: Rohm and Haas Company
- 当前专利权人地址: PA Philadelphia
- 主分类号: C07D333/38
- IPC分类号: C07D333/38 ; A61K31/16 ; A61K31/165 ; A61K31/166 ; A61K31/26 ; A61K31/27 ; A61K31/277 ; A61K31/34 ; A61K31/341 ; A61K31/38 ; A61K31/381 ; A61K31/42 ; A61K31/423 ; A61K31/425 ; A61K31/426 ; A61K31/428 ; A61K31/44 ; A61K31/4402 ; A61K31/4418 ; A61K31/455 ; A61P35/00 ; A61P43/00 ; C07C233/31 ; C07C237/30 ; C07C251/48 ; C07D213/81 ; C07D263/56 ; C07D275/02 ; C07D277/20 ; C07D277/32 ; C07D277/38 ; C07D307/58 ; A61K31/21 ; A61K31/15 ; A61K31/275
摘要:
A method for inhibiting mammalian cell growth is disclosed. The method uses compounds known as N-acetonylarylamides. The compounds have been shown to inhibit cell mitosis and to inhibit microtubule assembly. The method may be used to treat diseases associated with rapid cell growth, particularly cancer. The compounds used in the method of the present invention may be used in combination with other therapies and may be administered by known techniques for drug administration.
公开/授权文献
- US4712171A Electrical power source 公开/授权日:1987-12-08
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