发明授权
- 专利标题: DNA expression vectors for the use in the gene therapeutic treatment of vascular disorders
- 专利标题(中): 用于基因治疗治疗血管疾病的DNA表达载体
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申请号: US123624申请日: 1998-07-28
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公开(公告)号: US6149936A公开(公告)日: 2000-11-21
- 发明人: Jurgen Schrader , Axel Godecke
- 申请人: Jurgen Schrader , Axel Godecke
- 申请人地址: DEX Dusseldorf
- 专利权人: Schrader; Joseph
- 当前专利权人: Schrader; Joseph
- 当前专利权人地址: DEX Dusseldorf
- 优先权: DEX4411402 19940331
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K31/70 ; A61K38/00 ; A61K47/48 ; A61K48/00 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; C12N9/00 ; C12N9/02 ; C12N15/85 ; C12R1/91 ; A61K3/127 ; A61K31/7088
摘要:
A DNA expression vector is described which is characterized in that it comprises a DNA sequence that codes a protein which possesses the biological activity of nitrogen monoxide synthase (NOS) and eukaryotic regulation elements, wherein said eukaryotic regulation elements result in the expression of said DNA sequence in eukaryotic cells, as well as the use of the expression vector for treatment or prevention of vascular disorders.
公开/授权文献
- US5416666A Ergonomic operator workstation having monitor with wing unit 公开/授权日:1995-05-16
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