发明授权
- 专利标题： Death domain containing receptors
- 专利标题（中）： 含有受体的死亡域
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申请号： US815469申请日： 1997-03-11
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公开(公告)号： US6153402A公开(公告)日： 2000-11-28
- 发明人: Guo-Liang Yu , Jian Ni , Reiner L. Gentz , Patrick J. Dillon
- 申请人： Guo-Liang Yu , Jian Ni , Reiner L. Gentz , Patrick J. Dillon
- 申请人地址： MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： MD Rockville
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61P29/00 ; A61P31/04 ; A61P31/12 ; A61P35/00 ; A61P37/00 ; A61P43/00 ; C07H21/04 ; C07K14/705 ; C07K14/715 ; C12N1/21 ; C12N5/00 ; C12N5/10 ; C12N15/12 ; C12P21/02 ; C12R1/19 ; C12R1/91
摘要：
The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
公开/授权文献
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