发明授权
- 专利标题: Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
- 专利标题(中): 用于治疗糖尿病,血脂异常和高血压的二唑类物质:其制备方法和含有它们的药物组合物
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申请号: US134348申请日: 1998-08-14
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公开(公告)号: US6159966A公开(公告)日: 2000-12-12
- 发明人: Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Chennaveerappa Bajji , Shivaramayya Kalchar , Sekar Reddy Alla , Rajagopalan Ramanujam , Reeba Kannimel Vikramadithyan
- 申请人: Braj Bhushan Lohray , Vidya Bhushan Lohray , Ashok Chennaveerappa Bajji , Shivaramayya Kalchar , Sekar Reddy Alla , Rajagopalan Ramanujam , Reeba Kannimel Vikramadithyan
- 申请人地址: NJ Ridgewood INX Hyderabad
- 专利权人: Reddy-Cheminor Inc.,Dr. Reddy's Research Foundation
- 当前专利权人: Reddy-Cheminor Inc.,Dr. Reddy's Research Foundation
- 当前专利权人地址: NJ Ridgewood INX Hyderabad
- 优先权: INX1153/MAS 19970530
- 主分类号: C07D413/12
- IPC分类号: C07D413/12 ; C07D417/12 ; C07D417/14 ; A61K31/535 ; A61K31/54 ; C07D265/36 ; C07D279/16
摘要:
A compound of formula (I) ##STR1## its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates, wherein R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are the same or different; R.sup.1 and R.sup.2 together represent along with carbon atoms to which they are attached an aromatic cyclic structure containing 5-6 ring atoms which may optionally be substituted; X represents a heteroatom selected from oxygen or sulfur; R.sup.7 represents hydrogen atom, hydroxy, alkoxy, halogen, lower alkyl group or optionally substituted aralkyl group or forms a bond together with R.sup.8 ; R.sup.8 represents hydrogen atom, hydroxy, alkoxy, halogen, lower alkyl group or optionally substituted aralkyl or R.sup.8 forms a bond together with R.sup.7 ; B represents an oxygen atom or a sulfur atom; Y represents an oxygen atom or a sulfur atom, n is an integer ranging from 1 to 4 and m is an integer of zero or one, compositions containing compounds of formula (I) and methods of use of the compounds are described.
公开/授权文献
- US5468423A Reduced residue hard surface cleaner 公开/授权日:1995-11-21
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