发明授权
US06174998B1 C-nucleoside derivatives and their use in the detection of nucleic acids
失效
C-核苷衍生物及其在核酸检测中的应用
- 专利标题： C-nucleoside derivatives and their use in the detection of nucleic acids
- 专利标题（中）： C-核苷衍生物及其在核酸检测中的应用
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申请号： US08929068申请日： 1997-09-15
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公开(公告)号： US06174998B1公开(公告)日： 2001-01-16
- 发明人: Klaus M{umlaut over (u)}hlegger , Herbert Von der Eltz , Frank Seela , Helmet Rosemeyer
- 申请人： Klaus M{umlaut over (u)}hlegger , Herbert Von der Eltz , Frank Seela , Helmet Rosemeyer
- 主分类号： C07G1100
- IPC分类号： C07G1100
摘要：
The invention concerns pyrrolo-[3,2-d]pyrimidine, pyrazolo-[4,3-d]pyrimidine and pyrimidine-furanosides i.e. so-called C-nucleosides of the general formulae I-V or appropriate derivatives as well as processes for their production. The compounds are in particular suitable as substrates for RNA or DNA polymerases and can thus be incorporated into RNA or DNA oligonucleotides. Therefore the compounds are especially suitable for labelling and for detecting nucleic acids and for DNA sequencing.