发明授权
US06180784B2 Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
失效
用与两亲化合物和DNA结合蛋白质混合的多核苷酸转染细胞的方法
- 专利标题： Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
- 专利标题（中）： 用与两亲化合物和DNA结合蛋白质混合的多核苷酸转染细胞的方法
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申请号： US09020566申请日： 1998-01-17
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公开(公告)号： US06180784B2公开(公告)日： 2001-01-30
- 发明人: Jon A. Wolff , James E. Hagstrom , Vladimir G. Budker , Jeffery Fritz
- 申请人： Jon A. Wolff , James E. Hagstrom , Vladimir G. Budker , Jeffery Fritz
- 主分类号： C07D25502
- IPC分类号： C07D25502
摘要：
The present invention provides a process of transfecting a cell with a polynucleotide mixed with one or more amphipathic compounds and an effective amount of a DNA-binding protein. Exemplary and preferred DNA-binding proteins are H1, H2A, and H2B. Exemplary and preferred amphipathic compounds are cationic amphipathic compounds.
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