发明授权
- 专利标题： Apt-sensitive potassium channel gene-defective animals
- 专利标题（中）： 敏感钾通道基因缺陷动物
-
申请号： US09213864申请日： 1998-12-17
-
公开(公告)号： US06194634B1公开(公告)日： 2001-02-27
- 发明人: Susumu Seino , Takashi Miki , Junichi Miyazaki
- 申请人： Susumu Seino , Takashi Miki , Junichi Miyazaki
- 优先权： JP10-178097 19980610
- 主分类号： A01K67027
- IPC分类号： A01K67027
摘要：
A Kir6.2 gene-defective, non-human mammal, a mouse in particular, its tissues and cells are provided, wherein the ATP-sensitive potassium channel Kir6.2 gene, one of the subunits of KATP channels essential for insulin secretion by pancreatic &bgr;-cells, is lost from one or both of the allelic loci.