发明授权
- 专利标题： Process for preparing N-alkyl ammonium acetonitrile compounds
- 专利标题（中）： N-烷基铵乙腈化合物的制备方法
-
申请号： US09444041申请日： 1999-11-19
-
公开(公告)号： US06235218B1公开(公告)日： 2001-05-22
- 发明人: Ulrich Annen , James E. Deline , Lafayette D. Foland , Kevin A. Klotter , Josef Müller , Michael Müller , Klaus Mundinger , Martin A. Phillippi , Alfred Ruland , Wolfgang Schäfer , Gregor Schürmann , Rudi Widder , Alfred G. Zielske
- 申请人： Ulrich Annen , James E. Deline , Lafayette D. Foland , Kevin A. Klotter , Josef Müller , Michael Müller , Klaus Mundinger , Martin A. Phillippi , Alfred Ruland , Wolfgang Schäfer , Gregor Schürmann , Rudi Widder , Alfred G. Zielske
- 主分类号： C07D26530
- IPC分类号： C07D26530
摘要：
A process is provided for the preparation of a compound having the structure of Formula I The process includes reacting a heterocyclic amine with a monoaldehyde or a dialdehyde in a pH range of from about 8 to 14 and then quaternizing the so-reacted heterocyclic amine with an alkylating agent at a pH of not less than about 2. The use of pH control substantially prevents formation of an undesirable protonated reaction intermediate.
信息查询
