- 专利标题： Detection of nucleic acid hybrids
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申请号： US09358972申请日： 1999-07-21
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公开(公告)号： US06235480B1公开(公告)日： 2001-05-22
- 发明人: John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
- 申请人： John William Shultz , Martin K. Lewis , Donna Leippe , Michelle Mandrekar , Daniel Kephart , Richard Byron Rhodes , Christine Ann Andrews , James Robert Hartnett , Trent Gu , Ryan J. Olson , Keith V. Wood , Roy Welch
- 主分类号： C12Q168
- IPC分类号： C12Q168
摘要：
Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.