发明授权
US06242386B1 Process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof
失效
制备（1R，2S，4R） - （ - ） - 2 - [（2' - {N，N-二甲基氨基}乙氧基）] - 2- [苯基] -1,7,7-三 - [甲基 ] - 双环[2.2.1]庚烷及其药学上可接受的酸加成盐
![Process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof](/docs/US/2001-06-05/US06242386B1/abs.jpg.600x600.jpg)
- 专利标题： Process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof
- 专利标题（中）： 制备（1R，2S，4R） - （ - ） - 2 - [（2' - {N，N-二甲基氨基}乙氧基）] - 2- [苯基] -1,7,7-三 - [甲基 ] - 双环[2.2.1]庚烷及其药学上可接受的酸加成盐
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申请号： US09569050申请日： 2000-05-10
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公开(公告)号： US06242386B1公开(公告)日： 2001-06-05
- 发明人: Gyula Lukács , Gyula Simig , Tibor Mezei , Zoltán Budai , Márta Porcs-Makkay , György Krasznai , Kálmán Nagy , Györgyi Donáth Vereczkey , Tibor Szabó , Norbert Németh , János Szulágyi
- 申请人： Gyula Lukács , Gyula Simig , Tibor Mezei , Zoltán Budai , Márta Porcs-Makkay , György Krasznai , Kálmán Nagy , Györgyi Donáth Vereczkey , Tibor Szabó , Norbert Németh , János Szulágyi
- 优先权： HUP9901559 19990511
- 主分类号： C07C20900
- IPC分类号： C07C20900
![Process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof](/abs-image/US/2001/06/05/US06242386B1/abs.jpg.150x150.jpg)
摘要：
A process for preparing (1R,2S,4R)-(−)-2-[(2′-[N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo [2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof with higher yields and higher grades of purity.
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