发明授权
- 专利标题： Inhibitors of farnesyl-protein transferase
- 专利标题（中）： 法呢基蛋白转移酶抑制剂
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申请号： US09248883申请日： 1999-02-11
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公开(公告)号： US06248756B1公开(公告)日： 2001-06-19
- 发明人: Neville J. Anthony , Christopher Dinsmore , Robert P. Gomez , John H. Hutchinson , John S. Wai , Theresa M. Williams , Ian M. Bell , Mark W. Embrey , Thorsten E. Fisher
- 申请人： Neville J. Anthony , Christopher Dinsmore , Robert P. Gomez , John H. Hutchinson , John S. Wai , Theresa M. Williams , Ian M. Bell , Mark W. Embrey , Thorsten E. Fisher
- 主分类号： A61K314468
- IPC分类号： A61K314468
摘要：
The present invention is directed to compounds which inhibit farnesyl-protein transferas (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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