- 专利标题： Arylglycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
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申请号： US09507581申请日： 2000-02-18
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公开(公告)号： US06251909B1公开(公告)日： 2001-06-26
- 发明人: Gerd Schnorrenberg , Horst Dollinger , Franz Esser , Hans Briem , Birgit Jung , Georg Speck
- 申请人： Gerd Schnorrenberg , Horst Dollinger , Franz Esser , Hans Briem , Birgit Jung , Georg Speck
- 优先权： DE19514112 19950414; DE19519245 19950525
- 主分类号： A61K31495
- IPC分类号： A61K31495
摘要：
The invention relates to new arylglycinamide derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein R1 and R2 together with the N to which they are bound form a ring of the formula wherein p is 2 or 3 and X denotes oxygen, N(CH2)nR6 or CR7R8, and R3, R4, R5, R6, R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
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