Thieno pyridines and their use as anti-hypertensive agents
    4.
    发明授权
    Thieno pyridines and their use as anti-hypertensive agents 失效
    噻吩并吡啶类作为抗高血压药物

    公开(公告)号:US4826855A

    公开(公告)日:1989-05-02

    申请号:US199121

    申请日:1988-05-26

    摘要: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms);R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms);R.sub.3 is hydrogen or alkyl of 1 to 6 carbon atoms;n and m are each independently 0, 1 or 2, the sum of n and m being 1 or 2;X, Y and Z are each independently oxygen, sulfur, --NR.sub.4 --, .dbd.CR.sub.5 --, --CHR.sub.5 --, ##STR2## provided that only one of X, Y and Z is O, S, ##STR3## and one or two of X, Y and Z are --NR.sub.4 --; R.sub.4 is hydrogen or alkyl of 1 to 4 carbon atoms; andR.sub.5 is hydrogen or, together with a vicinal radical R.sub.5, a phenyl ring, or when m and n are both 1, the dihydro form with its double bond in conjugation with the C-term=inal carboxylic group;or a non-toxic, pharmacologically acceptable salt thereof. The compounds as well as their salts are useful as antihypertensives.

    摘要翻译: 其中R 1是氢,1至6个碳原子的烷基或苯基(1至6个碳原子的烷基)的式 R2是氢,1至4个碳原子的烷基或苯基(1至6个碳原子的烷基); R3是氢或1至6个碳原子的烷基; n和m各自独立地为0,1或2,n和m的和为1或2; X,Y和Z各自独立地为氧,硫,-NR4-,= CR5-,-CHR5-,,条件是X,Y和Z中只有一个是O,S,,一个或两个 X,Y和Z是-NR 4 - ; R4是氢或1-4个碳原子的烷基; 并且R 5是氢或与连位基R 5一起成为苯环,或者当m和n均为1时,其双键与C-term =内接羧基共轭的二氢形式; 或其无毒的药理学上可接受的盐。 化合物及其盐可用作抗高血压药。

    OUTDOOR LIGHTING UNIT
    10.
    发明申请
    OUTDOOR LIGHTING UNIT 审中-公开
    户外灯具

    公开(公告)号:US20120026737A1

    公开(公告)日:2012-02-02

    申请号:US13262760

    申请日:2010-03-30

    IPC分类号: F21V21/00 F21V29/00 F21V7/00

    摘要: The invention relates to an outdoor lighting unit for lighting streets, pavements, industrial grounds, and the like, comprising one LED light source which includes several light emitting diodes in a two-dimensional array, and a housing. The housing has a single-piece solid housing element, which has at least one planar assembly section on an underside, on which a backside of the LED light source is arranged in heat-conducting connection in a planar manner. The housing element further has on said underside a circumferential wall section, which projects downwardly from the plane of the assembly section. Further, the housing element comprises an exposed cooling section on an upper side, which is convexly curved and has several cooling channels, which extend along the convex curvature. The housing element also comprises a holding portion, by means of which the lighting unit can be secured to a holding device in a self-supporting manner.

    摘要翻译: 本发明涉及一种用于照明街道,路面,工业地面等的室外照明单元,包括一个LED光源,其包括二维阵列中的几个发光二极管和壳体。 壳体具有单件固体壳体元件,其在下侧具有至少一个平面组装部分,LED光源的背面以平面方式布置在导热连接中。 外壳元件还在所述下侧上具有周向壁部分,其从组件部分的平面向下突出。 此外,壳体元件包括在上侧上的暴露的冷却部分,该冷却部分凸起地弯曲并具有沿着凸曲率延伸的多个冷却通道。 壳体元件还包括保持部分,照明单元可以以自支撑的方式固定到保持装置。