发明授权
- 专利标题: Method for producing alcohols free of enantiomers
- 专利标题(中): 生产不含对映异构体的醇的方法
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申请号: US09331404申请日: 1999-06-21
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公开(公告)号: US06255087B1公开(公告)日: 2001-07-03
- 发明人: Christoph Dingler , Nicholas John Holman
- 申请人: Christoph Dingler , Nicholas John Holman
- 优先权: DE19707008 19970221
- 主分类号: C12P1716
- IPC分类号: C12P1716
摘要:
A process for preparing enantiomerically pure alcohols of the formula I (Ia or Ib) where the substituents have the following meanings: R1 hydrogen or substituted or unsubstituted C1-C6-alkyl, C1-C6-alkoxy or C1-C6-alkanoyl, R2 and R3 independently of one another hydrogen or substituted or unsubstituted C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkanoyl, C1-C6-alkylthio, C1-C6-alkylsulfinyl or C1-C6-alkylsulfonyl, R4 substituted or unsubstituted C1-C6-alkyl, C3-C8-cycloalkyl, which comprises reducing compounds of the formula II where the substituents R1 to R4 have the abovementioned meanings in aqueous solution in the presence of a carbon source and of a microorganism or of a reducing agent, of a cofactor and of an enzyme, to compounds of the formula I.
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