发明授权
- 专利标题： VEGF-binding polypeptide
- 专利标题（中）： VEGF结合多肽
-
申请号： US09051363申请日： 1998-07-15
-
公开(公告)号： US06270993B1公开(公告)日： 2001-08-07
- 发明人: Masabumi Shibuya , Masaji Okamoto , Mikio Niwa , Tomoe Matsumoto , Makoto Asano , Tosiaki Segawa
- 申请人： Masabumi Shibuya , Masaji Okamoto , Mikio Niwa , Tomoe Matsumoto , Makoto Asano , Tosiaki Segawa
- 优先权： JP7-286476 19951007; JP8-211892 19960723
- 主分类号： C07H2104
- IPC分类号： C07H2104
摘要：
An object of the present invention is to provide a low molecular weight VEGF inhibitor that can be utilized to treat diseases accompanying neovascularization, such as solid tumors. It was found that a polypeptide containing immunoglobulin-like domain 1 and immunoglobulin-like domain 2 but neither immunoglobulin-like main 6 nor immunoglobulin-like domain 7 of the extracellular domain of the VEGF receptor FLT possess VEGF inhibitory activity.
信息查询
