发明授权
- 专利标题: Over-coated chewing gum formulations including tableted center
- 专利标题(中): 涂覆过的口香糖配方包括压片中心
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申请号: US75983801申请日: 2001-01-11
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公开(公告)号: US6290985B2公开(公告)日: 2001-09-18
- 发明人: REAM RONALD L , CORRIVEAU CHRISTINE L , GRAFF GWENDOLYN , MATULEWICZ LEONARD
- 申请人: WRIGLEY W M JUN CO
- 优先权: US61880800 2000-07-18
- 主分类号: A23G3/34
- IPC分类号: A23G3/34 ; A23G4/00 ; A23G4/08 ; A23G4/20 ; A61K9/20 ; A61K9/24 ; A61K9/28 ; A61K9/36 ; A61K9/68 ; A61K47/10 ; A61K47/12 ; A61K47/18 ; A61K47/20 ; A61K47/22 ; A61K47/26 ; A61K47/36 ; A61K47/42 ; A61K47/46 ; A61P1/04 ; A61P3/02 ; A61P3/10 ; A61P9/00 ; A61P21/02 ; A61P25/18 ; A61P29/00 ; A61P31/04 ; A61P31/12 ; A61P43/00 ; A61K47/00
摘要:
Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
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