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公开(公告)号:US6290985B2
公开(公告)日:2001-09-18
申请号:US75983801
申请日:2001-01-11
申请人: WRIGLEY W M JUN CO
IPC分类号: A23G3/34 , A23G4/00 , A23G4/08 , A23G4/20 , A61K9/20 , A61K9/24 , A61K9/28 , A61K9/36 , A61K9/68 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/26 , A61K47/36 , A61K47/42 , A61K47/46 , A61P1/04 , A61P3/02 , A61P3/10 , A61P9/00 , A61P21/02 , A61P25/18 , A61P29/00 , A61P31/04 , A61P31/12 , A61P43/00 , A61K47/00
CPC分类号: A23G4/20 , A23G3/343 , A23G4/08 , A23G2200/04 , A61K9/0058 , A61K9/2086 , A61K9/209
摘要: Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
摘要翻译: 提供了将药物或药剂递送给个人的方法和产品以及用于生产该产品的方法。 该产品包括具有药物或试剂的涂层。 药物或药剂存在于围绕压片胶中心(水溶性部分和水不溶性基底部分)的涂层内。 通过咀嚼牙龈,药物或药剂从产品中释放出来。 继续咀嚼口香糖在口腔内产生压力,通过包含在口腔中的口腔粘膜,迫使药剂或药物直接进入个体的系统系统。 这大大增强了药物在系统系统中的吸收以及药物在系统内的生物利用度。