发明授权
US06294535B1 Uracil derivatives and antitumor effect potentiator and antitumor agent containing the same
有权
尿嘧啶衍生物和抗肿瘤作用增强剂和抗肿瘤药含有相同的作用
- 专利标题: Uracil derivatives and antitumor effect potentiator and antitumor agent containing the same
- 专利标题(中): 尿嘧啶衍生物和抗肿瘤作用增强剂和抗肿瘤药含有相同的作用
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申请号: US09457668申请日: 1999-12-09
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公开(公告)号: US06294535B1公开(公告)日: 2001-09-25
- 发明人: Shingo Yano , Yukio Tada , Hideki Kazuno , Tsutomu Sato , Junichi Yamashita , Norihiko Suzuki , Tomohiro Emura , Masakazu Fukushima , Tetsuji Asao
- 申请人: Shingo Yano , Yukio Tada , Hideki Kazuno , Tsutomu Sato , Junichi Yamashita , Norihiko Suzuki , Tomohiro Emura , Masakazu Fukushima , Tetsuji Asao
- 优先权: JP7-071667 19950329
- 主分类号: A61K31535
- IPC分类号: A61K31535
摘要:
The invention relates to novel uracil derivatives having excellent inhibiting effects on human derived thymidine phosphorylates and anti-tumor activity. The pharmaceutical compositions, anti-tumor potentiators and antitumor agents containing such novel compounds, and a process for their preparation and use are described. The novel uracil derivative compounds are represented by the general formula (1′):
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