发明授权
- 专利标题: Quinolone carboxylic acid derivatives
- 专利标题(中): 喹诺酮羧酸衍生物
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申请号: US09446697申请日: 1999-12-23
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公开(公告)号: US06313299B1公开(公告)日: 2001-11-06
- 发明人: Sung-Joon Yoon , Yong-Ho Chung , Chi-Woo Lee , Yoon-Seok Oh , Nam-Doo Kim , Jae-Kyung Lim , Yoon-Ho Jin
- 申请人: Sung-Joon Yoon , Yong-Ho Chung , Chi-Woo Lee , Yoon-Seok Oh , Nam-Doo Kim , Jae-Kyung Lim , Yoon-Ho Jin
- 优先权: KR97-27806 19970626; KR98-1609 19980120
- 主分类号: C07D48710
- IPC分类号: C07D48710
摘要:
The present invention relates to quinolonecarboxylic acid derivatives having more excellent and broad antibacterial activities than the existing quinolone-series antibiotics. More specifically, it pertains to novel quinolonecarboxylic acid derivatives represented by following formula 1, which have a derivative of 7-[8-(alkoxyimino)-2,6-diazaspiro[3.4]oct-6-yl] as a substituent, and pharmaceutically acceptable salts and isomers thereof: Wherein, A is C—H, C—F, C—Cl, C—O—CH3 or N; Y is H or amino; R1 is cyclopropyl or 2,4-difluorophenyl; R2 is C1-4 alkyl; and R3 is H or C1-4 alkyl.
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