发明授权
- 专利标题： Therapeutic and diagnostics proteins comprising a SOCS box
- 专利标题（中）： 包括SOCS盒的治疗和诊断蛋白质
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申请号： US09302769申请日： 1999-04-30
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公开(公告)号： US06323317B1公开(公告)日： 2001-11-27
- 发明人: Douglas J. Hilton , Warren S. Alexander , Elizabeth M. Viney , Tracy A. Willson , Rachael T. Richardson , Robyn Starr , Sandra E. Nicholson , Donald Metcalf , Nicos A. Nicola
- 申请人： Douglas J. Hilton , Warren S. Alexander , Elizabeth M. Viney , Tracy A. Willson , Rachael T. Richardson , Robyn Starr , Sandra E. Nicholson , Donald Metcalf , Nicos A. Nicola
- 优先权： AUP03384/96 19961101; AUP05117/97 19970214
- 主分类号： C07K100
- IPC分类号： C07K100
摘要：
The present invention relates generally to therapeutic and diagnostic agents. More particularly, the present invention provides therapeutic molecules capable of modulating signal transduction such as but not limited to cytokine-mediated signal transduction. The molecules of the present invention are useful, therefore, in modulating cellular responsiveness to cytokines as well as other mediators of signal transduction such as endogenous or exogenous molecules, antigens, microbes and microbial products, viruses or components thereof, ions, hormones and parasites.