发明授权
- 专利标题： 13-membered azalides and their use as antibiotic agents
- 专利标题（中）： 13-元氮杂ides啶及其作为抗生素的用途
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申请号： US09442530申请日： 1999-11-18
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公开(公告)号： US06329345B1公开(公告)日： 2001-12-11
- 发明人: Robert J. Rafka , Barry J. Morton , Colman B. Ragan , Peter Bertinato , John P. Dirlam , Alan E. Blize , Carl B. Ziegler
- 申请人： Robert J. Rafka , Barry J. Morton , Colman B. Ragan , Peter Bertinato , John P. Dirlam , Alan E. Blize , Carl B. Ziegler
- 主分类号： A61K3170
- IPC分类号： A61K3170
摘要：
The invention relates to a method of preparing compounds of the formula 1 and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
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