发明授权
US06399297B1 Antisense modulation of expression of tumor necrosis factor receptor-associated factors (TRAFs)
失效
肿瘤坏死因子受体相关因子(TRAF)表达的反义调节
- 专利标题: Antisense modulation of expression of tumor necrosis factor receptor-associated factors (TRAFs)
- 专利标题(中): 肿瘤坏死因子受体相关因子(TRAF)表达的反义调节
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申请号: US09167109申请日: 1998-10-06
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公开(公告)号: US06399297B1公开(公告)日: 2002-06-04
- 发明人: Brenda F. Baker , Lex M. Cowsert , Brett P. Monia , Xaoxing S. Xu
- 申请人: Brenda F. Baker , Lex M. Cowsert , Brett P. Monia , Xaoxing S. Xu
- 主分类号: C07H2104
- IPC分类号: C07H2104
摘要:
Compositions and methods are provided for modulating the expression of tumor necrosis factor receptor-associated factor (TRAF). Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding TRAF are preferred. Methods of using these compounds for modulation of TRAF expression and for treatment of diseases associated with expression of TRAF are provided.
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