发明授权
- 专利标题： Fibroblast growth factor-13
- 专利标题（中）： 成纤维细胞生长因子-13
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申请号： US08976315申请日： 1997-11-21
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公开(公告)号： US06403557B1公开(公告)日： 2002-06-11
- 发明人: John M. Greene , Joachim R. Gruber , Craig A. Rosen
- 申请人： John M. Greene , Joachim R. Gruber , Craig A. Rosen
- 主分类号： A61K3818
- IPC分类号： A61K3818
摘要：
The present invention relates to a novel FGF-13 protein which is a member of the fibroblast growth factor (FGF) family. In particular, isolated nucleic acid molecules are provided encoding the human FGF-13 protein. FGF-13 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of FGF-13 activity. Also provided are diagnostic methods for detecting FGF-13-related disorders and therapeutic methods for treating FGF-13-related disorders. Disclosed is a method of prolonging dopaminergic neuron survival.