发明授权
US06492335B1 Glycoconjugates from modified camptothecin derivatives (20-O-linkage)
失效
来自改性喜树碱衍生物（20-O-键）的糖缀合物
- 专利标题： Glycoconjugates from modified camptothecin derivatives (20-O-linkage)
- 专利标题（中）： 来自改性喜树碱衍生物（20-O-键）的糖缀合物
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申请号： US09269317申请日： 1999-03-24
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公开(公告)号： US06492335B1公开(公告)日： 2002-12-10
- 发明人: Hans-Georg Lerchen , Karsten von dem Bruch , Jörg Buamgarten , Michael Sperzel
- 申请人： Hans-Georg Lerchen , Karsten von dem Bruch , Jörg Buamgarten , Michael Sperzel
- 优先权： DE19640206 19960930; DE19643764 19961023
- 主分类号： A61K3170
- IPC分类号： A61K3170
摘要：
The present invention relates to glycoconjugates of camptothecin derivatives in which at least one carbohydrate component is linked via suitable spacers with the 20-hydroxyl group of a camptothecin derivative. The invention furthermore relates to processes for preparing the compounds according to the invention and to their use as medicaments, in particular in connection with cancer.
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