发明授权
- 专利标题： Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
- 专利标题（中）： 神经氨酸酶的五元碳环和杂环抑制剂
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申请号： US09422093申请日： 1999-10-19
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公开(公告)号： US06518305B1公开(公告)日： 2003-02-11
- 发明人: Clarence J. Maring , Yuanwei Chen , David A. Degoey , Vincent L. Giranda , David J. Grampovnik , Yu Gui Gu , Warren M. Kati , Dale J. Kempf , April Kennedy , Allan C. Krueger , Zhen Lin , Darold L. Madigan , Steven W. Muchmore , Hing L. Sham , Kent D. Stewart , Vincent S. Stoll , Minghua Sun , Gary T. Wang , Sheldon Wang , Ming C. Yeung , Chen Zhao
- 申请人： Clarence J. Maring , Yuanwei Chen , David A. Degoey , Vincent L. Giranda , David J. Grampovnik , Yu Gui Gu , Warren M. Kati , Dale J. Kempf , April Kennedy , Allan C. Krueger , Zhen Lin , Darold L. Madigan , Steven W. Muchmore , Hing L. Sham , Kent D. Stewart , Vincent S. Stoll , Minghua Sun , Gary T. Wang , Sheldon Wang , Ming C. Yeung , Chen Zhao
- 主分类号： A61K31195
- IPC分类号： A61K31195
摘要：
Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.