A semiconductor memory device includes isolation circuits disconnecting cell arrays from sense amplifiers, and isolation signal generating circuits generating isolation signals that control the isolation circuits. The isolation signal generating circuits are hierarchically divided into main isolation signal generating circuits and sub isolation signal generating circuits. The sub isolation signal generating circuits generate sub isolation signals having a first potential on a high-potential side. The main isolation signal generating circuits generate main isolation signals having a second potential on the high-potential side, the second potential being lower than the first potential.