发明授权
- 专利标题： Pyridine derivatives
- 专利标题（中）： 吡啶衍生物
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申请号： US09956618申请日： 2001-09-18
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公开(公告)号： US06562811B1公开(公告)日： 2003-05-13
- 发明人: Toshiki Murata , Masaomi Umeda , Sachiko Sakakibara , Takashi Yoshino , Hiroki Sato , Tsutomu Masuda , Yuji Koriyama , Mitsuyuki Shimada , Takuya Shintani , Hiroshi Kadono , Timothy B. Lowinger , Karl B. Ziegelbauer , Kinji Fuchikami , Hiroshi Komura
- 申请人： Toshiki Murata , Masaomi Umeda , Sachiko Sakakibara , Takashi Yoshino , Hiroki Sato , Tsutomu Masuda , Yuji Koriyama , Mitsuyuki Shimada , Takuya Shintani , Hiroshi Kadono , Timothy B. Lowinger , Karl B. Ziegelbauer , Kinji Fuchikami , Hiroshi Komura
- 优先权： JP2000-289173 20000922
- 主分类号： A61K3154
- IPC分类号： A61K3154
摘要：
Pyridine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 alkoxycarbonyl, C1-6 alkylamino, di(C1-6 alkyl)amino, C1-6 alkanoylamino, phenyl C1-6 alkylamino, phenylsulfonylamino, or —O—(CH2)n—R111; R2 represents hydrogen or halogen; R3 represents hydrogen, —CR31R32R33, or —NR34R35; R4 is hydrogen, carbamoyl, CN, carboxyl, etc.; R5 is amino, C1-6 alkylamino, di C1-6 alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.
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