发明授权
US06570015B2 Process for producing 2-substituted thiopyrimidine-4-carboxylate
失效
制备2-取代硫代嘧啶-4-羧酸酯的方法
- 专利标题： Process for producing 2-substituted thiopyrimidine-4-carboxylate
- 专利标题（中）： 制备2-取代硫代嘧啶-4-羧酸酯的方法
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申请号： US10245571申请日： 2002-09-17
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公开(公告)号： US06570015B2公开(公告)日： 2003-05-27
- 发明人: Akio Matsushita , Kiyotaka Yoshii , Masayoshi Oue , Taku Nakamura , Shuji Yamada
- 申请人： Akio Matsushita , Kiyotaka Yoshii , Masayoshi Oue , Taku Nakamura , Shuji Yamada
- 优先权： JP2001-284635 20010919
- 主分类号： C07D23938
- IPC分类号： C07D23938
摘要：
There is disclosed a process for producing a 2-substituted thiopyrimidine-4-carboxylate represented by the formula (3): wherein R2 represents a substituted or unsubstituted hydrocarbon group and R3 represents a hydrocarbon group, which comprises reacting-an &agr;-keto ester compound represented by the formula (1): R1OCH═CHCOCO2R2 (1) wherein R1 represents a substituted or unsubstituted hydrocarbon group, and R has the same meaning as defined above, with an isothiourea compound represented by the formula (2): wherein R3 has the same meaning as defined above.
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